Effect of Long-Term Cadmium Intoxication on Selected Biochemical Parameters in Experimental Animals
نویسندگان
چکیده
Cadmium (Cd) is a dangerous occupational and environmental toxin. Exceeding its permissible weekly uptake in meals is a disturbing phenomenon. The aim of this study is to assess the effect of long-term uptake of cadmium chloride on selected biochemical parameters and oxidative stress biomarkers in animal models. Long-term intoxication with cadmium chloride elevated blood serum concentration of urea, creatinine, glucose, AspAT and A1AT activity as well as TBARS and protein carbonyl group concentrations; TBARS concentration in erythrocytes was also elevated as well as 8-hydroxy-2'-deoxyguanosine excretion with urine.
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